… Remarkably, even mice lacking all mediators critical for p53-induced apoptosis, G1/S …
which p53 induces cell death and how this affects p53-mediated tumour suppression and …

… utilized by CTLs to induce apoptosis of target cells (23). This … , and upregulates the apoptosis
receptor Fas/APO-1. Thus, this … , differentiation, and recruitment of T-cells (25). However, if a …

… The best-described target for E6 is the p53 tumor suppressor … p53 is necessary in MG132
and APO-1-induced apoptosis. … Statistical evaluation of significant differences was performed …

… crucial roles in early development and differentiation of the … induced apoptosis of several
different types of cancer [166]. miR-21 also negatively regulates PTEN, a tumor suppressor gene…

… , inhibitors of apoptosis proteins (IAPs), tumor suppressor (p53) in cancer cells along with
various current clinical approaches aimed to selectively induce apoptosis in cancer cells. …

… apoptomiRs, oncomiR or tumor suppressor miRNAs in different … MiR-195, miR-24-2, and
miR-365-2 induce apoptosis by … -13-acetate (PMA)-induced differentiation of ML-1 cells, an …

… these differences in transcriptional induction of target genes … of the tumor necrosis factor
receptor (TNFR) family (FAS/APO-1/… important mediators of TP53-induced apoptosis, there may …

… effective in inducing apoptosis on … apoptosis rate of ovarian cancer HO-8910 cells. Western
blot analysis was utilized to measure the levels of apoptotic proteins such as p53, Fas/APO-1, …

… methylated derivative of PRIMA-1, inhibited mutant p53 … -1 for inducing cell death in a mutant
p53-dependent manner is … to the upregulation of p53, death receptor Fas/APO-1, and Fas …

… tumor suppressor gene, P53 promotes the repair of DNA damage. In cases where the damage
cannot be successfully repaired, P53 induces apoptosis … a differentiation-inducing drug for …